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Articles (31)
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1

Postmortem transcriptional profiling reveals widespread increase in inflammation in schizophrenia: a comparison of prefrontal cortex, striatum, and hippocampus among matched tetrads of controls with subjects diagnosed with schizophrenia, bipolar or major depressive disorder

Lanz, Thomas A., Reinhart, Veronica, Sheehan, Mark J., Rizzo, Stacey J. Sukoff, Bove, Susan E., James, Larry C., Volfson, Dmitri, Lewis, David A., Kleiman, Robin J.

Journal:

Translational Psychiatry

Année:

2019

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2019

2

Inhibitors of cAMP and cGMP phosphodiesterases enhance neurite outgrowth from cultured cortical neurons in a PKG dependent manner

Lida Kimmel, Mary Collins, Christopher J Schmidt, Frank Menniti, Robin Kleiman

Journal:

BMC Pharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 179 KB

english, 2007

3

Regulation of cGMP by phosphodiesterases (PDEs) in the central nervous system

Frank S Menniti, Robin J Kleiman, Christopher J Schmidt

Journal:

BMC Pharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 179 KB

english, 2007

4

Chronic treatment with a selective inhibitor of casein kinase I δ/ε yields cumulative phase delays in circadian rhythms

Jeffrey Sprouse, Linda Reynolds, Robin Kleiman, Barbara Tate, Terri A. Swanson, Gary E. Pickard

Journal:

Psychopharmacology

Année:

2010

Langue:

english

Fichier:

PDF, 623 KB

english, 2010

5

Testing the Agrin Hypothesis

Robin J. Kleiman, Louis F. Reichardt

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 801 KB

english, 1996

6

Application of Structure-Based Drug Design and Parallel Chemistry to Identify Selective, Brain Penetrant, In Vivo Active Phosphodiesterase 9A Inhibitors

Claffey, Michelle M., Helal, Christopher J., Verhoest, Patrick R., Kang, Zhijun, Fors, Kristina S., Jung, Stanley, Zhong, Jiaying, Bundesmann, Mark W., Hou, Xinjun, Lui, Shenping, Kleiman, Robin J., V

Journal:

Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2012

7

Overexpression of human tau induces loss of synaptic markers and requires phosphorylation of tau in the microtubule binding domain

Carol D. Hicks, Tracy M. Brown, Lida H. Kimmel, Robin J. Kleiman, Karl E.G. Richter, Paula Loos

Journal:

Alzheimer's & Dementia

Année:

2010

Langue:

english

Fichier:

PDF, 39 KB

english, 2010

8

PDE9A-MEDIATED REGULATION OF CGMP: IMPACT ON SYNAPTIC PLASTICITY

Frank Menniti, Robin Kleiman, Christopher Schmidts

Journal:

Schizophrenia Research

Année:

2008

Langue:

english

Fichier:

PDF, 72 KB

english, 2008

9

Temperature-dependent blockade of nucleocytoplasmic transport of newly synthesized RNA in neurons

Kleiman, Robin, Banker, Gary, Steward, Oswald

Journal:

Molecular Brain Research

Année:

1992

Langue:

english

Fichier:

PDF, 6.67 MB

english, 1992

10

Differential subcellular localization of particular mRNAs in hippocampal neurons in culture

Kleiman, Robin, Banker, Gary, Steward, Oswald

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 915 KB

english, 1990

11

Select 3′,5′-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain

Kelly, Michy P., Adamowicz, Wendy, Bove, Susan, Hartman, Alexander J., Mariga, Abigail, Pathak, Geetanjali, Reinhart, Veronica, Romegialli, Alison, Kleiman, Robin J.

Journal:

Cellular Signalling

Année:

2014

Langue:

english

Fichier:

PDF, 2.07 MB

english, 2014

12

PDE9A-mediated regulation of cGMP: Developing a biomarker for a novel therapy for Alzheimer's disease

Schmidt, Christopher J., Harms, John F., Tingley, F. David, Schmidt, Kari, Adamowicz, Wendy O., Romegialli, Alison, Kleiman, Robin J., Barry, Chris J., Coskran, Timothy M., O'Neill, Sharon M., Stephen

Journal:

Alzheimer's & Dementia

Année:

2009

Langue:

english

Fichier:

PDF, 46 KB

english, 2009

13

Subcellular distribution of rRNA and poly(A) RNA in hippocampal neurons in culture

Kleiman, Robin, Banker, Gary, Steward, Oswald

Journal:

Molecular Brain Research

Année:

1993

Langue:

english

Fichier:

PDF, 936 KB

english, 1993

14

Dendritic spine density deficits in the hippocampal CA1 region of young Tg2576 mice are ameliorated with the PDE9A inhibitor PF-04447943

Kleiman, Robin J., Lanz, Thomas A., Finley, James E., Bove, Susan E., Majchrzak, Mark J., Becker, Stacey L., Carvajal-Gonzales, Santos, Kuhn, A. Max, Wood, Kathleen M., Mariga, Abigail, Nelson, Freder

Journal:

Alzheimer's & Dementia

Année:

2010

Langue:

english

Fichier:

PDF, 62 KB

english, 2010

15

Identification of a Brain Penetrant PDE9A Inhibitor Utilizing Prospective Design and Chemical Enablement as a Rapid Lead Optimization Strategy

Verhoest, Patrick R., Proulx-Lafrance, Caroline, Corman, Michael, Chenard, Lois, Helal, Christopher J., Hou, Xinjun, Kleiman, Robin, Liu, Shenping, Marr, Eric, Menniti, Frank S., Schmidt, Christopher

Journal:

Journal of Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 3.28 MB

english, 2009

16

Evaluation of TrkB and BDNF transcripts in prefrontal cortex, hippocampus, and striatum from subjects with schizophrenia, bipolar disorder, and major depressive disorder

Reinhart, Veronica, Bove, Susan E., Volfson, Dmitri, Lewis, David A., Kleiman, Robin J., Lanz, Thomas A.

Journal:

Neurobiology of Disease

Année:

2015

Langue:

english

Fichier:

PDF, 1011 KB

english, 2015

17

Therapeutics for cognitive aging

Shineman, Diana W., Salthouse, Timothy A., Launer, Lenore J., Hof, Patrick R., Bartzokis, George, Kleiman, Robin, Luine, Victoria, Buccafusco, Jerry J., Small, Gary W., Aisen, Paul S., Lowe, David A.,

Journal:

Annals of the New York Academy of Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 150 KB

english, 2010

18

On Crowd-verification of Biological Networks

Hoeng, Julia, Ansari, Sam, Kleiman, Robin, Binder, Jean, Hayes, William, Iskandar, Anita, Rhrissorrakrai, Kahn, Norel, Raquel, O'Neel, Bruce, Peitsch, Manuel, Poussin, Carine, Talikka, Marja, Schlage,

Journal:

Bioinformatics and Biology Insights

Année:

2013

Langue:

english

Fichier:

PDF, 4.99 MB

english, 2013

19

Inhibition of Protein Synthesis Alters the Subcellular Distribution of mRNA in Neurons but Does not Prevent Dendritic Transport of RNA

Robin Kleiman, Gary Banker and Oswald Steward

Journal:

Proceedings of the National Academy of Sciences

Année:

1993

Langue:

english

Fichier:

PDF, 1.46 MB

english, 1993

20

TSC2 controls neuronal development through FOXO1 and mitochondrial function in Autism Spectrum Disorders patient derived human neurons

Han, Min-Joon, Hoyo, Leonie, Kleiman, Robin, Sahin, Mustafa

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 47 KB

english, 2015

21

Overlapping 16p13.11 deletion and gain of copies variations associated with childhood onset psychosis include genes with mechanistic implications for autism associated pathways: Two case reports

Brownstein, Catherine A., Kleiman, Robin J., Engle, Elizabeth C., Towne, Meghan C., D'Angelo, Eugene J., Yu, Timothy W., Beggs, Alan H., Picker, Jonathan, Fogler, Jason M., Carroll, Devon, Schmitt, Ra

Journal:

American Journal of Medical Genetics Part A

Année:

2016

Langue:

english

Fichier:

PDF, 398 KB

english, 2016

22

A novel de novo mutation in ATP1A3 and childhood-onset schizophrenia

Smedemark-Margulies, Niklas, Brownstein, Catherine A., Vargas, Sigella, Tembulkar, Sahil K., Towne, Meghan C., Shi, Jiahai, Gonzalez-Cuevas, Elisa, Liu, Kevin X., Bilguvar, Kaya, Kleiman, Robin J., Ha

Journal:

Molecular Case Studies

Année:

2016

Langue:

english

Fichier:

PDF, 1.67 MB

english, 2016

23

De novo ATP1A3 and compound heterozygous NLRP3 mutations in a child with autism spectrum disorder, episodic fatigue and somnolence, and muckle-wells syndrome

Torres, Alcy, Brownstein, Catherine A., Tembulkar, Sahil K., Graber, Kelsey, Genetti, Casie, Kleiman, Robin J., Sweadner, Kathleen J., Mavros, Chrystal, Liu, Kevin X., Smedemark-Margulies, Niklas, Mas

Journal:

Molecular Genetics and Metabolism Reports

Année:

2018

Langue:

english

Fichier:

PDF, 753 KB

english, 2018

24

Best Practices for Translational Disease Modeling Using Human iPSC-Derived Neurons

Engle, Sandra J., Blaha, Laura, Kleiman, Robin J.

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2018

25

BDNF-Induced Potentiation of Spontaneous Twitching in Innervated Myocytes Requires Calcium Release From Intracellular Stores

Kleiman, Robin J., Tian, Ning, Krizaj, David, Hwang, Thomas N., Copenhagen, David R., Reichardt, Louis F.

Journal:

Journal of Neurophysiology

Année:

2000

Langue:

english

Fichier:

PDF, 571 KB

english, 2000

26

Withdrawn Article

Torres, Alcy, Brownstein, Catherine A., Tembulkar, Sahil K., Graber, Kelsey, Genetti, Casie, Kleiman, Robin J., Sweadner, Kathleen, Liu, Kevin X., Mavros, Chrystal, Smedemark-Margulies, Niklas, Agrawa

Journal:

Molecular Genetics and Metabolism Reports

Année:

2019

Langue:

english

Fichier:

PDF, 41 KB

english, 2019

27

Comparison of Outcomes After Transcatheter vs Surgical Aortic Valve Replacement Among Patients at Intermediate Operative Risk With a History of Coronary Artery Bypass Graft Surgery

Reardon, Michael J., Heijmen, Robin H., Van Mieghem, Nicolas M., Williams, Mathew R., Yakubov, Steven J., Watson, Daniel, Kleiman, Neal S., Conte, John, Chawla, Atul, Hockmuth, David, Petrossian, Geor

Journal:

JAMA Cardiology

Année:

2019

Langue:

english

Fichier:

PDF, 203 KB

english, 2019

28

A Pilot Study on the Effects of Physician Gaze on Patient Satisfaction in the Setting of Electronic Health Records

Ou, Michael T., Kleiman, Hannah, Kalarn, Sachin, Moradi, Ahmadreza, Shukla, Shweta, Danielson, Madalyn, Kaleem, Mona, Boland, Michael, Robin, Alan L., Saeedi, Osamah J.

Journal:

Journal of Academic Ophthalmology

Année:

2019

Langue:

english

Fichier:

PDF, 140 KB

english, 2019

29

How to develop therapeutic and translational research collaborations with industry

Kleiman, Robin J., Ehlers, Michael D., Bement, William

Journal:

Molecular Biology of the Cell

Année:

2019

Langue:

english

Fichier:

PDF, 51 KB

english, 2019

30

How to develop therapeutic and translational research collaborations with industry

Kleiman, Robin J., Ehlers, Michael D., Bement, William

Journal:

Molecular Biology of the Cell

Année:

2019

Fichier:

PDF, 51 KB

2019

31

Phenotypic Screen with TSC-Deficient Neurons Reveals Heat-Shock Machinery as a Druggable Pathway for mTORC1 and Reduced Cilia

Di Nardo, Alessia, LenoÃ«l, Isadora, Winden, Kellen D., RÃ¼hmkorf, Alina, Modi, Meera E., Barrett, Lee, Ercan-Herbst, Ebru, Venugopal, Pooja, Behne, Robert, Lopes, Carla A.M., Kleiman, Robin J., Bette

Journal:

Année:

2020

Fichier:

PDF, 4.76 MB

2020